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ß Cell of the Pancreas producing insulin


Electricity and ATP

Normal function of Pancreas ß cell. When needed the cell is able to emit a sufficient amount of insulin into the bloodstream.



















In case of the development of diabetes under insulin resistant conditions the flow of electrons/protons through the ATP-synthase is disturbed.
A so called uncoupling protein (UCP) is induced during the etiology of the disease. These UCP’s divert the electrons/ protons away from the ATP-synthase so that the electrons/protons still flow from the inter-membrane space towards the inner-membrane space but they do not generate ATP.
As a result heat is produced instead of the useful energy ATP.

Development of